MSc Medical Laboratory Technology in clinical chemistry

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branches in India in the recent past There is always increased demand competition. urge to improve their own quality Many clinical laboratories now going for NABL. accreditation and maintaining quality at low cost is being taken up as a challenge now a. days especially in the field of clinical chemistry Hence there is lots of scope and. opportunity for those who are willing to perceive this course. Annexure 1,Course Structure curriculum, Faculty for the course Course coordinator Prof R Ramesh. Coordinator Dr G Niranjan, Faculty Prof Saha S Prof Srinivasan A R Dr Sathish B M Dr Reeta R Dr Swetha K. Evaluation pattern,Examinations, Duration of theory examination for all the papers will be three hours each. Practical and viva examinations for MSc MLT clinical chemistry are. conducted in two consecutive days, Internal assessment Internal Assessment will be based on formative. assessment examinations projects log books records presentation of. seminars and journal clubs and work assessment during clinical postings. and tutorials In the case of candidates who fail in the University. examination fresh internal assessment marks can be sent based on their. improvement in their performances, There shall be Four examiners for practical and viva two internal and.
two external External examiner should be a regular teaching faculty of. any medical college with either a MD degree or MSc PhD in. Biochemistry MLT and should be Associate Professor and above Theory. papers will be evaluated by both external and internal examiners. Question paper setters, Should be a regular teaching faculty of any medical college with either a. MD degree or MSc PhD in Biochemistry MLT,Setting up of Question Paper. Each theory paper will be of 3 hours duration with a Maximum of 100. marks Theory paper in all the subjects will consist of 2 sections Section. A B Each section carries 50 marks and shall consist of an essay. question with 10 marks 7 question carrying 4 marks each and 6 questions. carrying 2 marks each Section A B will have to be answered in. separate answer booklets, Failed Candidates Candidate failing to secure minimum pass 50 in. any paper Theory or practicals shall reappear for both theory and. practicals, References Syllabus of MSc MLT form JIPMER KMC Manipal VEER. NARMAD SOUTH GUJARAT UNIVERSITY and SURAT,Suggested books.
Biochemistry by Geoffrey L Zubay Fourth Edition 1998. Fundamentals of Biochemistry by Donald Voet Judith Voet and Pratt second. edition 1995,Biochemistry Lubert Stryer, Harper s Biochemistry by Murray etal Appleton and Lange Publishers 27h. edition 2006, Principles of Biochemistry by Lehninger Nelson and Cox fourth edition W H. Freeman and Company New York USA 2005, Textbook of Biochemistry by West and Todd Fourth Edition 1966. Text book of clinical chemistry Teitz, Varley s Practical Clinical Biochemistry by Alan H Gowenlock published by. CBS Publishers and distributors India Sixth Edition. Practical Biochemistry Wilson Walker,Clinical chemistry Marshal.
Clinical Biochemistry Principle and Practice Praful B Godkar. Lecture notes on Clinical chemistry L G Whitby,Clinical Chemistry Kaplan. Clinical chemistry in diagnosis and treatment Philip D Mayne. Clinical Chemistry Michael L Bishop,NMS Biochemistry. Immunology Janis Kuby fourth edition W H Freeman Company USA 2000. Essential Immunology Ivan Roitt Blackwell Science Publishers UK 1997. A Hand Book of Practical Immunology GP Talwar Vikas Publishing House 1983. Many more under the respective sections,Composition of board of studies. The board of study members,External Members,1 Prof B D Toora HOD AVMC RC Puducherry. 2 Dr Medha Associate Professor Dept Of Biochemistry JIPMER. Puduchery Internal members Prof Saha S Prof Srinivasav A R Dr. Sathish Babu M Dr Reeta R Dr Swetha K, MSc in Medical Laboratory Technology in clinical chemistry.
Faculty of medical sciences,FIRST YEAR 3 PAPERS,TOTAL MARKS 600. PAPER 1 Biomolecules Metabolism Research methodology and. biostatistics 100 marks, PAPER 2 Enzymology Biophysical chemistry Vitamins minerals and. basics of Nutrition 100 marks,PAPER 3 Clinical Biochemistry Part I 100marks. Practicals 200 marks, Internal Assessment 50 marks Theory 25 Practicals 25. VIVA 50 marks,SECOND YEAR,TOTAL MARKS 600, PAPER 1 Basics of Endocrinology Clinical Immunology Cell.
Molecular Biology human genetics 100 marks, PAPER 2 Medical Laboratory Techniques instrumentation 100. PAPER 3 Clinical Biochemistry Part 1I 100 marks,Practicals 200 marks. VIVA Dissertation Viva 30 marks Theory Viva 20 marks 50. Internal Assessment 50 marks Theory 25 Practicals 25. COURSE CONTENT,FIRST YEAR, PAPER 1 Biomolecules Metabolism Biophysical chemistry and. Enzymology 100 marks,BIOMOLECULES, Introduction Introduction to Biochemistry water as biological solvent weak acids and. bases pH buffers Handerson Hasselbalch equation physiological buffers. Carbohydrates Classification structure occurrence and biological functions. Physicochemical properties of monosaccharides, Lipids Classification structure occurrence and biological functions of lipids Nomenclature.
and properties of fatty acids and triglycerides saponification number acid. number Reichert Meissel number rancidity of fats Composition and types of. lipoproteins Steroids and carotenoids of biological origin liposomes. Amino acids Nomenclature classification and chemical structure of amino acids. Physicochemical properties of amino acids with their titration curve reaction with. ninhydrin amino acids as zwitterions and isoelectric point. Proteins Classification structure primary secondary tertiary and quaternary structure. of peptide bond Ramachandran Plot properties and biological functions of. proteins Protein denaturation renaturation Methods to determine amino acid. sequence N and C terminal amino acid identification amino acid sequencing of. small peptides and overlapping Chemical synthesis of polypeptides salting in and. salting out of proteins, Nucleic acids Nature of genetic material properties of DNA in solution evidence of. DNA as genetic material and evidence for semi conservative nature Composition of. RNA and DNA generalized structure plan of nucleic acids nomenclature in structure. of nucleic acids features of DNA double helix denaturation and annealing of DNA. Structure and roles of different types of DNAs and RNAs Genetic code genome. Porphyrins Porphyrin nucleus and classification of prophyrins important metalloporphyrins. occurring in nature Chemical nature and significance of bile pigments. Suggested Readings, 1 Lehninger Principles of Biochemistry 4th Ed By David L Nelson and Michael M Cox. WH Freeman and Company, 2 Chemistry of Biomolecules an Introduction Paperback By Richard J Simmonds. Publisher Royal Society of Chemistry, 3 Principles of Biochemistry Hardcover By Geoffrey Zubay Publisher McGraw Hill. 4 Biochemistry By Lubert Stryer WH Freeman and Co, 5 Biochemistry The Molecular Basis of Life Paperback By Trudy McKee and James R.
McKee Publisher McGraw Hill Higher education, 6 Biochemistry and Molecular biology By William H Elliott and Daphne C Elliott. Oxford University Press, 7 Biochemistry Hardcover 3rd Ed By Donald J Voet and Judith G Voet John Wiley. 8 Biochemistry Biomolecules Mechanisms of Enzyme Action and Metabolism Vol 1. Hardcover By D Voet John Wiley and Sons, 9 Fundamentals of Biochemistry Life at the Molecular Level Import Hardcover. By Donald Voet Judith G Voet and Charlotte W Pratt Publisher Wiley. 10 Principles of Biochemistry Paperback By Robert Horton Laurence A Moran Gray. Scrimgeour Marc Perry and David Rawn Pearson Education. 11 Biochemistry By U S Satyanarayana, 12 Outlines of Biochemistry By Eric C Conn PK Stumpf G Bruening and Ray H Doi. John Wiley Sons,METABOLISM, Introduction Concept of metabolism experimental approaches to study metabolismuse.
of intact organisms bacterial mutants tissue slices and radioisotopes. ETC and Oxidative phosphorylation Sequence of electron carriers sites of ATP production. inhibitors of ETC mechanism and regulation of mitochondrial oxidative. phosphorylation ATP synthase uncouplers of oxidative phosphorylation transport of. reducing potential and ions across mitochondrial membrane phosphorylation. potential reversed and microsomal electron transfers generation of superoxides in. mitochondria, Carbohydrate Metabolism Reactions and energetics of glycolysis Alcoholic and lactic. fermentations entry of fructose mannose and galactose Reactions and energetics of. TCA cycle gluconeogenesis glycogenesis and glycogenolysis Reactions and. physiological significance of HMP pathway regulation of glycolysis and gluconeogenesis. cataplerosis and anaplerosis biosynthesis of starch and oligosaccharides. regulation of blood glucose Uronic acid pathway and glyoxylate cycle. Lipid metabolism Transport and mobilization of lipids oxidation of saturated fatty. acids oxidation of unsaturated and odd chain fatty acids role of carnitine. in transport of fatty acid energetics of oxidation scheme metabolism of ketone. bodies and its biological significance Biosynthesis of saturated and unsaturated fatty acids. Biosynthesis of triglycerides phospholipids sphingolipids and cholesterol Regulation of. cholesterol metabolism Metabolism of lipoproteins Biosynthesis of prostaglandins. Amino acid metabolism General reactions of amino acid metabolism transamination. deamination and oxidative decarboxylation Biosynthesis and degradation of. amino acids and their regulation Feedback regulation of amino acid biosynthesis Urea. cycle and its regulation, Nucleic acid Metabolism Sources of atoms in purine and pyrimidine molecules. biosynthesis, and degradation of purines and pyrimidines regulation of purine and. pyrimidine biosynthesis structure and regulation of ribonucleotide reductase Biosynthesis. of ribonucleotides deoxyribonucleotides and polynucleotides Inhibitors of. nucleic acid biosynthesis Porphyrin Metabolism Biosynthesis and degradation of. porphyrins production of bile pigments,Suggested Readings. 1 Lehninger Principles of Biochemistry 4th Ed By David L Nelson and Michael M Cox. WH Freeman and Company, 2 Principles of Biochemistry Hardcover By Geoffrey Zubay Publisher McGraw Hill.
3 Harper s Biochemistry Lange Medical Books Paperback By Robert K Murray Daryl. K Granner Peter A Mayes and Victor W Rodwell Publisher Appelton and Lange. 4 Bioenergetics By David G Nicholls and Stuart J Ferguson Academic Press. 5 Bioenergetics at a Glance An Illustrated Introduction At a Glance Paperback By D. A Harris Publisher Wiley Blackwell, 6 Bioenergetics 0 Paperback By Lars Garby and Poul S Larsen Cambridge University. 7 Fundamentals of Biochemistry Life at the Molecular Level Import Hardcover. By Donald Voet Judith G Voet and Charlotte W Pratt Publisher Wiley. 8 Biochemistry Hardcover 3rd Ed By Donald J Voet and Judith G Voet John Wiley. 9 Biochemistry of Lipids Lipoproteins and Membranes 4th Ed D E Vance and J E. Vance Pub Elsevier Science B V, 10 Medical Biochemistry 4th Ed by NV Bhagavan Pub Elsevier India Pvt Ltd. 11 Biochemistry Biomolecules Mechanisms of Enzyme Action and Metabolism Vol 1. Hardcover By D Voet John Wiley and Sons, 12 Biochemistry By Lubert Stryer WH Freeman and Co. 13 Principles of Biochemistry Paperback By Robert Horton Laurence A Moran Gray. Scrimgeour Marc Perry and David Rawn Pearson Education. 14 Harper s Biochemistry By RK Murray DK Granner PA Mayes and VW Rodwell. Appelton and Lange Stanford,15 Biochemistry By U S Satyanarayana. 16 Outlines of Biochemistry By Eric C Conn PK Stumpf G Bruening and Ray H Doi. John Wiley Sons,Biophysical chemistry, Cell the cell organelles membrane structure of bio membrane transport across bio.
membranes the fluid mosaic model of bio membranes surface tension viscosity Donnan. membrane equilibrium osmosis diffusion osmotic pressure oncotic pressure. Enzymology, Introduction History general characteristics nomenclature IUB classification definitions. with examples of holoenzyme apoenzyme coenzymes prosthetic groups. cofactors activators inhibitors active site metalloenzymes isozymes monomeric. enzymes oligomeric enzymes and multienzyme complexes Units of enzyme activity. definition of IU Katal specific activity of enzyme measurement of enzyme activity. enzyme turnover Ribozymes and abzymes, Enzyme Catalysis Role of enzymes in energy of activation factors of affecting action. of enzymes proximity and orientation strain and distortion acid base catalysis and. covalent catalysis Determination of active site Mechanism of action of chymotrypsin. ribonuclease carboxypeptidase and lysozyme, Enzyme kinetics Factors affecting enzyme activity pH temperature time of incubation. enzyme concentration and substrate concentration Derivation of Michaelis. Menten equation for unisubstrate reaction Kcat Km and its significance Lineweaver. Burk plot and its limitations Eadie Hofstee Plot Eadie Plot Hanes plot and Eisenthal. Cornish Bowden plot Significance and calculation of energy of activation from. Arrhenius plot Reversible and irreversible inhibition competitive non competitive. and uncompetitive inhibitions with determination of Km and Vmax in presence of. reversible inhibitor Derivation of Ki and Dixon plot Kinetics of multisubstrate. any medical college with either a MD degree or MSc PhD in Biochemistry MLT and should be Associate Professor and above Theory papers will be evaluated by both external and internal examiners Question paper setters Should be a regular teaching faculty of any medical college with either a MD degree or MSc PhD in Biochemistry MLT

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